Joint Commission and Coalition for Health AI (CHAI) Release Initial Guidance to Support Responsible AI Adoption Across U.S. Health Systems
First set of national guidance helps U.S. healthcare organizations prepare for the growing role of AI in care delivery
OAKBROOK TERRACE, Illinois, Sept. 17, 2025 (GLOBE NEWSWIRE) -- Today, Joint Commission and the Coalition for Health AI (CHAI) released the first installment of their work together – Guidance on Responsible Use of AI in Healthcare, which will serve as internal governance to help U.S. health systems safely and effectively implement artificial intelligence (AI) at scale. This guidance represents the first of many milestones to result from their strategic partnership, launched June 2025.
“We understand how quickly AI is changing healthcare – and at a scale I’ve never seen in my time as a leader,” said Dr. Jonathan Perlin, president and CEO of Joint Commission. “From the moment we announced our partnership with CHAI, we knew we wanted our partnership to reflect that fast-paced dynamic, while still delivering a thoughtful and streamlined guidance for healthcare organizations to self-govern with AI.”
This guidance, which features high-level recommendations for the Responsible Use of AI and is designed to be accessible, applicable, and adaptable for healthcare organizations at any stage of their AI journey. Specifically, it establishes that policies, appropriate local validation, monitoring, and use, to be flexibly interpreted and integrated into existing or new processes as deemed appropriate for the context of any organization. This guidance is meant to provide transparency into the Joint Commission-CHAI process, and community feedback on this guidance will be incorporated into future outputs.
“The need is immediate, and we are eager to respond,” said Dr. Brian Anderson, CEO of CHAI. “This guidance and all subsequent playbooks are about keeping pace with the evolving field, not just by defining responsible AI, but by making it usable in hospitals and health systems across the country – no matter their resource level.”
A series of products are slated to launch later this year and into 2026. The next release will be governance playbooks, after a series of workshops are conducted to ensure hospitals and health systems of all sizes and regions are contributing to its development. These playbooks will be built on the original guidance, incorporating the feedback received from the community, and providing more practical and applied details. Following that, Joint Commission will develop a voluntary AI certification based on the final set of playbooks and open it to its more than 22,000 accredited and certified healthcare organizations nationwide.
Joint Commission’s evidence-based standards, reach, and scale, combined with CHAI’s technical expertise and broad-based network, provides the unique ability to guide health systems in effectively utilizing AI to improve patient outcomes. Further, the ongoing partnership will foster increased innovation within expert and field-driven guidelines and guardrails, more productivity and reduced administrative burden on providers, and overall better health outcomes.
The guidance is publicly available here: https://www.jointcommission.org/en-us/about-us/key-initiatives/ai-data-analytics-research.
About Joint Commission
Joint Commission enables and affirms the highest standards of healthcare quality and patient safety for all. Founded in 1951, it is the nation’s oldest and largest standards-setting and accrediting body in healthcare, evaluating more than 23,000 healthcare organizations and programs across the United States. As an independent, nonprofit organization, Joint Commission inspires healthcare organizations across all settings to excel in providing safe and effective care of the highest quality and value. Learn more at www.jointcommission.org.
About Coalition for Health AI (CHAI)
The CHAI (Coalition for Health AI) mission is to be the trusted source of guidelines for responsible AI in health that serves all. It aims to ensure high-quality care, foster trust among users, and meet the growing healthcare needs. CHAI membership is open and rapidly expanding with nearly 3000 organizations including health systems, patient advocacy groups, and a wide range of industry leaders and start-ups across the healthcare and technology ecosystems. CHAI is committed to convening and dialogue to achieve consensus. There is no limit to who can join and participate. Learn more about a CHAI membership here.

Katie Bronk The Joint Commission 630-792-5175 press@jointcommission.org Andrea Heuer Coalition for Health AI (CHAI) 917-914-5563 CHAI@12080group.com
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